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Doxycycline. Phenobarbital has long been shown to shorten the half-lifetime of doxycycline for so long as two weeks following barbiturate therapy is discontinued.Most reports of clinically substantial drug interactions transpiring Together with the barbiturates have concerned phenobarbital. Nevertheless, the application of these info to other barbi

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Contraindicated. Coadministration not advised; powerful cytochrome P450 enzyme inducers minimize systemic exposure to roflumilast and should reduce the therapeutic performanceB: May be appropriate. Both animal scientific tests exhibit no danger but human scientific tests not readily available or animal scientific tests showed small risks and human

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